MDAiRE is a skincare brand by Stefani Kappel MD, a board certified, double fellowship trained Dermatologist and Mohs Micrographic Surgeon. ARE is an acronym for an important signal transduction pathway in the skin, which stands for Antioxidant Response Element. The "i" in science represents "the induction of." Hence, AiRE represents the activation of this powerful anti-aging pathway. Backed by science. Doctor developed. Research driven. USA owned. Shop MDAiRE on Skin Truth today!